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規(guī)格	庫(kù)存	目錄價(jià)	會(huì)員專享價(jià)	數(shù)量
5 mg	3-5days	￥336.00	登錄后可見(jiàn)	- +
10 mg	3-5days	￥576.00	登錄后可見(jiàn)	- +

規(guī)格

庫(kù)存

目錄價(jià)

會(huì)員專享價(jià)

數(shù)量

5 mg

3-5days

￥336.00

登錄后可見(jiàn)

- +

10 mg

3-5days

￥576.00

登錄后可見(jiàn)

- +

基本信息

英文名稱	Omipalisib \| GSK2126458 \| GSK458
中文名稱	GSK2126458
CAS號(hào)	1086062-66-9
分子式	C25H17F2N5O3S
分子量	505.50
外觀	Off-white to yellow powder
儲(chǔ)存條件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

產(chǎn)品詳情

Omipalisib (GSK2126458, GSK458) is a highly selective and potent inhibitor of p110α/β/δ/γ, mTORC1/2 with Ki of 0.019 nM/0.13 nM/0.024 nM/0.06 nM and 0.18 nM/0.3 nM in cell-free assays, respectively. Omipalisib induces autophagy.

相關(guān)文獻(xiàn)

Combinations of BRAF, MEK, and PI3K/mTOR inhibitors overcome acquired resistance to the BRAF inhibitor GSK2118436 dabrafenib, mediated by NRAS or MEK mutations.

PMID: 22389471 DOI: 10.1158/1535-7163.MCT-11-0989

PMID: 24900173 PMCID: PMC4007793 DOI: 10.1021/ml900028r

PMID: 23899692 PMCID: PMC3800496 DOI: 10.1021/cb400430t

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CL1337

GSK2126458

1086062-66-9 98+% 3-5days

￥336.00 5 mg

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GSK2126458

Omipalisib | GSK2126458 | GSK458

化學(xué)品安全說(shuō)明書(MSDS)